Metoclopramide HCl Injection

Description

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Dosage Strengths
Metoclopramide HCl Injection (2 mL Vial) †5 mg/mL (10 mg / 2 mL)

† commercial product

About Metoclopramide HCl Injection

Metoclopramide may help move food through the digestive system and prevent nausea.^[1] It is related to the drug procainamide, but it does not have anesthetic or antiarrhythmic effects.^[2] It may assist adults with diabetic stomach problems and GERD when other treatments don’t work.^[3] Metoclopramide injections may help prevent nausea and vomiting after surgery or during chemotherapy, help with small bowel intubation, or assist with digestion during radiographic exams.^[4]

Metoclopramide may cause tardive dyskinesia (TD), a serious movement disorder.^[3] The risk of TD increases with longer use, so treatment should not exceed 12 weeks.^[3] Using metoclopramide in children may be controversial due to a higher risk of TD and other movement disorders, as well as the risk of methemoglobinemia in newborns.^[2]

Storage

Store this medication at 68°F to 77°F (20°C to 25°C) and away from heat, moisture and light. Keep all medicine out of the reach of children. Throw away any unused medicine after the beyond use date. Do not flush unused medications or pour down a sink or drain.

References

1. Mayo Clinic. “Metoclopramide (Oral Route).” Available at: https://www.mayoclinic.org/drugs-supplements/metoclopramide-oral-route/description/drg-20064784– LinkOpens in New Tab
2. Metoclopramide. Clinical Pharmacology powered by ClinicalKey. Elsevier. Updated June 10, 2024. Accessed June 24, 2024. https://www.clinicalkey.com/pharmacology/monograph/757?sec=mondesc– LinkOpens in New Tab
3. Isola S, Hussain A, Dua A, Singh K, Adams N. Metoclopramide. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023 Sep 4. Available from: https://www.ncbi.nlm.nih.gov/books/NBK519517/#:~:text=Metoclopramide%20is%20a%20dopamine%20receptor,gastroparesis%20by%20increasing%20gastric%20motility.– LinkOpens in New Tab
4. Drugs.com. “Metoclopramide Monograph.” Available at: https://www.drugs.com/monograph/metoclopramide.html